报告题目1： Noncoding RNA Sequences: Trash or Treasure?
报告人：赵文学
报告时间： 2014年4月2日（周三） 下午 14:30——15:30
报告地点：水产与生命学院A211
报告人简介：
赵文学 博士 美国加州大学旧金山分校 助理研究员
2008年博士毕业于中国科学院遗传与发育生物学研究所，2008-2013在加州大学旧金山分校做博士后研究，2013年至今在加州大学旧金山分校做助理研究员，研究兴趣主要集中于非编码序列调控元件的注释。在包括Nature Biotechnology，Stem Cells，Biomaterials等国际知名期刊发表了多篇有重要学术影响力的文章。
报告题目2：Creating Sense from Non-sense DNA: De Novo Genesis and Evolutionary History of the Antifreeze Glycoprotein Gene in Northern Cod Fishes
报告人：Dr. Xuan Zhuang (University of Illinois at Urbana-Champaign)
报告时间：2014年4月8日（周二） 下午14:00--15:00
报告地点：水产与生命学院A211
报告人简介：
Xuan Zhuang earned her B.S. and M.S in Marine Biology from Xiamen University where her thesis work focused on evolution of grouper mitochondrial genomes. Moving across the Pacific Ocean to the United States, Xuan completed her Ph.D. in Evolutionary Biology at University of Illinois at Urbana-Champaign and is currently working as a postdoctoral research associate in the lab of Dr. Chris Cheng and Dr. Art DeVries. Her research interest is origin and evolution of new genes, especially those novel genes with adaptive function that can be linked to natural selection. Her dissertation investigated the evolutionary origin, mechanism and history of antifreeze glycoprotein (AFGP) gene in Arctic and northern cod fishes.
Xuan Zhuang earned her B.S. and M.S in Marine Biology from Xiamen University where her thesis work focused on evolution of grouper mitochondrial genomes. Moving across the Pacific Ocean to the United States, Xuan completed her Ph.D. in Evolutionary Biology at University of Illinois at Urbana-Champaign and is currently working as a postdoctoral research associate in the lab of Dr. Chris Cheng and Dr. Art DeVries. Her research interest is origin and evolution of new genes, especially those novel genes with adaptive function that can be linked to natural selection. Her dissertation investigated the evolutionary origin, mechanism and history of antifreeze glycoprotein (AFGP) gene in Arctic and northern cod fishes.
报告内容：
The prevailing paradigm of new gene creation underlying evolutionary innovation predicates on duplication of a pre-existing ancestral gene, and through adaptive sequence change in one copy a new trait may emerge. De novo genes were previously thought to be extremely rare, if they could even occur at all. In my talk, I will discuss the genomic origin and evolutionary mechanism of a novel gene in Arctic and northern cod fishes, antifreeze glycoprotein (AFGP) gene, which evolved from non-coding DNA. This study tests the intriguing hypothesis of sense from non-sense DNA evolution of an important life-saving novel gene, where mutation and natural selection have evidently forged open reading frames and functional promoters out of raw genomic DNA. It provides a clear example of radical de novo origination of an entire gene family of vital adaptive function that can be directly linked to environmental selection.
The prevailing paradigm of new gene creation underlying evolutionary innovation predicates on duplication of a pre-existing ancestral gene, and through adaptive sequence change in one copy a new trait may emerge. De novo genes were previously thought to be extremely rare, if they could even occur at all. In my talk, I will discuss the genomic origin and evolutionary mechanism of a novel gene in Arctic and northern cod fishes, antifreeze glycoprotein (AFGP) gene, which evolved from non-coding DNA. This study tests the intriguing hypothesis of sense from non-sense DNA evolution of an important life-saving novel gene, where mutation and natural selection have evidently forged open reading frames and functional promoters out of raw genomic DNA. It provides a clear example of radical de novo origination of an entire gene family of vital adaptive function that can be directly linked to environmental selection.
（水产与生命学院）